Dr. Addai has several years of experience as a patent agent at MBHB and, after recently graduating from law school, is joining MBHB as an associate. In addition to her patent prosecution experience, Dr. Addai has provided technological advice in support of validity, infringement, and patentability litigation and opinions in the biotechnology, pharmaceutical and diagnostics areas.
Prior to joining MBHB, Dr. Addai was a graduate researcher at Meharry Medical College. Dr. Addai worked in biochemistry, immunology and virology developing expertise in a variety of molecular and biochemical techniques including molecular cloning and mutagenesis, protein expression and purification, virus propagation, genetic manipulation of microorganisms, immunoassays, flow cytometry, quantitative PCR and mass spectrometry. She served as a research analyst at the University of Notre Dame Office of Technology Transfer wherein she evaluated the patentability of disclosures, conducted marketability searches, and identified potential commercial partners. Under the USPTO Law School Clinic Certification Pilot Program, she served as a certified legal intern at the University of Notre Dame Intellectual Property and Entrepreneurship Clinic where she interviewed and counseled clients on various intellectual property related issues, performed patentability searches and drafted patent applications.
J.D., Loyola University Chicago School of Law
Ph.D., Meharry Medical College,
Biomedical Science (Biochemistry); High Honors; Doctoral Thesis: “Cocaine Enhances HIV-1 Integration in CD4+ T Cells by Modulating the Epigenetic DNA Signatures of Host Genome.”
M.S., University of Notre Dame,
B.A., University of Tennessee - Knoxville,
U.S. Patent & Trademark Office
American Society of Biochemistry and Molecular Biology
American Society of Hematology
Society of NeuroImmune Pharmacology
American Association of Cancer Research
Balasubramaniam M, Zhou J, Addai A, Martinez P, Pandhare J, Aiken C, Dash C (2018). PF74 Inhibits HIV-1 Integration by Altering The Composition of the Preintegration Complex. J Virol. pii: JVI.01741-18.
Balasubramaniam, M., Davids, B., Addai, A.B., Pandhare, J., and Dash, C. (2017). Measurement of in vitro integration activity of HIV-1 preintegration complex. J. Vis. (120), 54581.
Addai, A.B., Pandhare, J., Paromov, V., Mantri, C.K., Pratap, S., and Dash, C. (2015). Cocaine directly modulates HIV-1 integration in primary CD4+ T cells: Implications in HIV-1 pathogenesis among drug abusing patients. J Leukoc Biol 97(4): 779-790.
Pandhare, J., Addai, A.B., Mantri, C.K., Hager, C., Smith, R.M., Barnett, L., Villalta, F., Kalams, S.A., and Dash, C. (2014). Cocaine enhances HIV-1-induced CD4 (+) T-cell apoptosis: implications in disease progression in cocaine- abusing HIV-1 patients. Am J Pathol 184, 927-936.
Walker, S.A., Addai, A.B., Mathis, M., and Ramesh, A. (2007). Effect of dietary fat on metabolism and DNA adduct formation after acute oral exposure of F-344 rats to fluoranthene. J Nutr Biochem 18:236-249.