Joshua Bosman is a senior patent agent with McDonnell Boehnen Hulbert & Berghoff LLP. Dr. Bosman provides technological advice in support of validity, infringement, and patentability analysis in the biotechnology area.
Prior to joining MBHB, Dr. Bosman was a Postdoctoral Research Fellow at the University of Chicago where he was appointed to the NIH funded Cardiovascular Sciences Training Program. He also served as a discussion facilitator at the University of Chicago in which he conducted small group discussions with medical students on clinical case studies.
Dr. Bosman serves as a TreeKeeper in Chicago as part of the Openlands Project. In doing so, he is certified to plant trees and help maintain the urban forests of Chicago parks and coordinates and instructs other volunteers for habitat restoration projects in Chicago.
Dr. Bosman served as a science fair judge for a number of years in which he evaluated the science projects of students at Lincoln Park High School and Murray Language Academy in Chicago.
B.S., Calvin College,
Ph.D., Northwestern University,
Cancer Biology, Doctoral Research: Ets1 Regulation of alphaB-Crystallin and Involvement in Breast Cancer Cell Transformation.
Postdoctoral Fellowship, University of Chicago,
Research: Investigated the Hedgehog-mediated molecular networks required for atrial septation in the developing mouse heart.
U.S. Patent & Trademark Office
Friedland-Little JM, Hoffmann AD, Ocbina PJ, Peterson MA, Bosman JD, Chen Y, Cheng SY, Anderson KV, Moskowitz IP. A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus. Hum Mol Genet. 2011 Jun 8.
Evans JR, Bosman JD, Brown-Endres L, Yehiely F, Cryns VL. Induction of the small heat shock protein alphaB-crystallin by genotoxic stress is mediated by p53 and p73. Breast Cancer Res Treat. 2010 Jul;122(1):159-68. Epub 2009 Sep 24. PubMed Central PMCID: PMC2883682.
Bosman JD, Yehiely F, Evans JR, Cryns VL. Regulation of alphaB-crystallin gene expression by the transcription factor Ets1 in breast cancer. Breast Cancer Res Treat. 2010 Jan;119(1):63-70. Epub 2009 Feb 11. PubMed PMID: 19205872. PubMed Central PMCID: PMC2791186.
Lu M, Strohecker A, Chen F, Kwan T, Bosman J, Jordan VC, Cryns VL. Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels. Clin Cancer Res. 2008 May 15;14(10):3168-76. PubMed PMID: 18483385.
Westerheide SD, Bosman JD, Mbadugha BN, Kawahara TL, Matsumoto G, Kim S, Gu W, Devlin JP, Silverman RB, Morimoto RI. Celastrols as inducers of the heat shock response and cytoprotection. J Biol Chem. 2004 Dec 31;279(53):56053-60. Epub 2004 Oct 26. PubMed PMID: 15509580.